Skip to product information
NAD+
  • NAD+
  • NAD+
  • NAD+
Third Party Test Report
AmeiliaP

I have been taking NAD for a new months now and am sleeping through the night, and have more energy through the day
NAD+

Pure NAD+ Capsules 500mg

NAD+ supplements boost your NAD+ levels, enhancing energy, slowing ageing, and supporting metabolism.
Pack Size
In stock
One-time purchase at full price. No subscription required.
NAD+
120 Capsules

Free delivery on all orders over £50

90 Day Money Back Guarantee

Cellular Repair
Cellular Repair
Increase Energy
Increase Energy
Capsule Size
500mg
Daily Dose
1-2 Capsules
Shelf Life
2 Years
Ingredients per capsule
Nicotinamide Adenine Dinucleotide
Purity: Purity: 99.96% (third party tested)
NO Artificial Ingredients, Wheat, Gluten, Yeast, Soy, Corn, Dairy or Preservatives.
Third Party Test Report

What are NAD+ Supplements?

NAD, or nicotinamide adenine dinucleotide, is a crucial coenzyme found in every living cell. It is essential for the transfer of energy from nutrients to the cell's energy currency, ATP, playing a pivotal role in metabolism. NAD exists in two forms: NAD+ and NADH, which are involved in oxidative and reductive reactions, respectively, within the cell. This molecule is fundamental not only for energy production but also for the regulation of cellular processes and ageing.

The Science Behind NAD+ Supplements

NAD (nicotinamide adenine dinucleotide) is a crucial coenzyme in cells, vital for energy generation. It exists as NAD+ (oxidized) and NADH (reduced), transitioning between these states to transfer electrons during cellular respiration. NAD+ picks up electrons, becoming NADH, which then contributes these electrons to the electron transport chain to produce ATP, the cell's energy currency. This cycle is essential for cellular energy and health. Hence why NAD supplements are so popular.

NAD+
Benefits

  • Enhanced Metabolism

    NAD+ plays a critical role in converting food into energy by participating in redox reactions within the mitochondria, the powerhouses of the cell. This helps maintain vital energy levels across bodily functions.

  • Cellular Repair

    NAD+ is essential for the activation of PARPs (poly ADP-ribose polymerases), enzymes that help repair DNA damage. Increased NAD+ levels can boost the body's ability to repair its DNA, contributing to cellular health and longevity.

  • Neurological Health

    NAD+ is involved in brain function and has been shown to support neurological health. It can enhance cognitive function and has been researched for its potential to slow the progression of neurodegenerative diseases like Alzheimer's and

  • Aging and Longevity

    NAD+ levels naturally decrease with age, affecting cellular metabolism and health. Supplementing with NAD+ precursors like nicotinamide riboside can help replenish NAD+ levels, potentially slowing down the aging process and improving lifespan.

  • Regulates Circadian Rhythm

    NAD+ influences the body's circadian rhythms by modulating the activity of sirtuins, a group of enzymes that regulate biological clocks in response to light cues and metabolic signals.

  • Healthy Metabolism

    Adequate levels of NAD+ are crucial for maintaining overall metabolic health, influencing processes such as fat metabolism, preventing metabolic disorders, and supporting a healthy weight.

How NAD+ Works

1

Electron Acceptance

NAD+ acts as an electron acceptor in various metabolic pathways. During these reactions, NAD+ picks up two electrons and a proton to become NADH. This transformation is crucial as it helps to harvest energy from nutrients like glucose, fats, and proteins that are broken down in different metabolic pathways such as glycolysis and the Krebs cycle.

2

Electron Transport Chain Contribution

Once NADH is formed, it carries the electrons to the mitochondria, where it donates these electrons to the electron transport chain (ETC). This chain is a series of protein complexes embedded in the inner mitochondrial membrane that use the electron's energy to pump protons across the membrane.

3

Synthesizing ATP

The proton gradient created by the ETC drives the synthesis of ATP through a process known as oxidative phosphorylation. ATP synthase, an enzyme, uses the flow of protons back across the membrane to convert ADP (adenosine diphosphate) and phosphate into ATP (adenosine triphosphate), the primary energy currency of the cell.

Questions, anyone?

Need help with something? Here are our most frequently asked questions.

  • What are NAD+ supplements and how do they work?

    NAD+ supplements aim to increase the levels of Nicotinamide Adenine Dinucleotide (NAD+) in the body. NAD+ is a vital coenzyme found in all living cells, playing a key role in energy metabolism and cellular function. It participates in redox reactions essential for converting nutrients into cellular energy (ATP). NAD+ also activates enzymes called sirtuins that are involved in DNA repair and gene expression. As we age, NAD+ levels naturally decline, and supplements like NMN (Nicotinamide Mononucleotide) or NR (Nicotinamide Riboside) are used to boost these levels, potentially supporting cellular health.

  • What are the potential benefits of taking NAD+ supplements?

    Potential benefits of NAD+ supplements include enhanced energy metabolism, improved mitochondrial function, and activation of enzymes that support DNA repair and cellular health. Some users report increased energy levels, better cognitive function, and improved overall vitality. By replenishing declining NAD+ levels, these supplements may help support healthy aging processes.

  • Are NAD+ supplements safe to take?

    NAD+ supplements are generally considered safe for most healthy individuals when taken at recommended dosages. Common forms like NMN and NR have been studied and found to be well-tolerated. Mild side effects such as nausea, fatigue, or digestive discomfort may occur in some cases. It's crucial to consult a healthcare professional before starting NAD+ supplements, if you are pregnant, breastfeeding, have underlying health conditions, or are taking other medications.

  • How should I take NAD+ supplements and what is the recommended dosage?

    • There is no universally established dosage for NAD+ supplements, as optimal amounts can vary based on individual factors like age, health status, and specific health goals. Common dosages for NMN and NR supplements range from 250 mg to 500 mg per day. It's essential to follow the manufacturer's instructions on the product label and consult with a healthcare provider to determine the appropriate dosage for your needs.

  • Are there any side effects or risks associated with NAD+ supplements?

    While NAD+ supplements are generally safe, some individuals may experience side effects such as mild gastrointestinal issues, headaches, dizziness, or fatigue. High doses may increase the likelihood of side effects.

  • Can NAD+ supplements slow down ageing?

    NAD+ supplements are thought to support processes associated with healthy ageing by enhancing cellular functions like DNA repair and energy metabolism. By boosting NAD+ levels, they may activate sirtuins and other enzymes that promote cellular health. While animal studies have indicated potential anti-aging effects, human research is still in the early stages. Therefore, while NAD+ supplements may support certain aspects of cellular health, they should not be considered a definitive solution for slowing down ageing.